IZKF-Project J59

IZKF

Head of Department:
Prof. Dr. med. André Reis

Immunotoxin induced anti-tumor immunity

Preclinical and first clinical data suggest that treatment with recombinant immunotoxin (rITs) targeting mesothelin induced anti-tumor immunity in patients. The goal of this study is to test CD22-targeting rITs for their capacity of inducing anti-lymphoma immunity in a newly established syngeneic mouse model. The model will be used to understand molecular mechanisms central to the lymphoma-host-interaction and to optimize immune-modulating combination treatment based on lymphoma-targeting rITs.

Dr. Fabian Müller
phone: +49 9131 85-39542
e-mail: fabian.mueller@uk-erlangen.de
business card
 
Term

01.07.2017 - 31.12.2019

Project Manager

Dr. Fabian Müller

Department of Medicine 5

 
 
 
 
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Summary