IZKF-Project J51

IZKF

Head of Department:
Prof. Dr. med. André Reis

Inflammatory signature in Parkinson’s disease

In Parkinson’s disease (PD), peripheral monocytes and the CN immune system, namely microglia and astroglia play an important inflammatory role in mediating disease progression. The hypothesis of this proposal is that the inflammatory profile of these cells in human PD and its models is altered. I aim to characterize the distinct monocytic, microglial and astroglial phenotypes and their interactions. Moreover, the anti-inflammatory effects of the flavone apigenin will be analyzed.

 
Term

01.10.2015 - 31.03.2018

Project Manager

Dr. Franz Marxreiter

Department of Neurology

 
 
 
 
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Summary