IZKF-Project J60

IZKF

Head of Department:
Prof. Dr. med. André Reis

The role of Hck/Lyn in Vesicles secretion

In recent work I detected that plasma extracellular vesicles (pEV) from HIV-infected individuals and tumor patients contain either significant amounts of Hck or Lyn. In the here presented grant proposal we suggest to investigate the molecular mechanism behind this finding. We will (1) analyze the molecular interactions of Hck and Lyn with identified factors of the pEV secretion complex, and (2) clarify at which subcellular compartment these molecular events take place.

Dr. Jung-Hyun Lee
phone: +49 9131 85-39530
business card
 
Term

01.10.2016 - 31.03.2019

 

Project Manager

Dr. Jung-Hyun Lee

Department of Dermatology

 
 
 
 
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Summary