IZKF-Project J56

IZKF

Head of Department:
Prof. Dr. med. André Reis

Epigenetic reprogramming of macrophages

Our preliminary data show that recognition of apoptotic cells (ACs) by macrophages dramatically affects chromatin remodelling processes within these phagocytes, resulting in an anti-inflammatory macrophage phenotype. We hypothesize that these events essentially contribute to the non-immunogenic clearance of dying cells. In the proposed project, we plan to dissect the underlying molecular mechanisms and determine the role of these pathway during the the resolution of injury-induced inflammation.

Dr. Katrin Palumbo-Zerr
phone: +49 9131 85-39352
DECT: +49 9131 85-43044
fax: +49 9131 85-33011
e-mail: katrin.palumbo@uk-erlangen.de
business card
 
Term

01.01.2017 - 30.06.2019

Project Manager

Dr. Katrin Palumbo Zerr

Department of Medicine 3

 
 
 
 
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Summary