IZKF-Project E25

IZKF

Head of Department:
Prof. Dr. med. André Reis

Human nociceptors

Our aim is to understand the role of the sodium channel subtype Nav1.9 in pain syndroms. Fibroblasts from patients with hereditary pain syndromes due to Nav1.9  mutations will be reprogrammed into hiPSC and differentiated to nociceptors. Using electrophysiological and molecular methods, we will monitor the development of excitability in these neurons in order to understand mechanisms of nociception and the role of Nav1.9 in the development of human pain.

Prof. Dr. Beate Winner
phone: +49 9131 85-39301
e-mail: beate.winner@fau.de
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Prof. Dr. med. Dr. h. c. Jürgen Schüttler
phone: +49 9131 85-33676
e-mail: juergen.schuettler@kfa.imed.uni-erlangen.de
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Term

01.07.2016 - 31.12.2018

Project Manager

Prof. Dr. Beate Winner

IZKF Junior Research Group 3


Prof. Dr. Dr. h. c. Schüttler

Department of Anaesthesiology

 
 
 
 
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Summary