IZKF-Project E24

IZKF

Head of Department:
Prof. Dr. med. André Reis

a-synuclein during inflammatory demyelination

Increasing evidence indicates that neuroinflammatory and -degenerative disorders are far more interconnected than previously assumed. Since intracellular alpha-synuclein (a-syn) aggregates in synucleinopathies affects the maturation of primary oligodendrocyte progenitor cells, the project will investigate the hypothesis whether a-syn has a detrimental role for myelin homeostasis in a prototypical model of multiple sclerosis with inflammation and demyelination in the central nervous system.

Prof. Dr. Jürgen Winkler
phone: +49 9131 85-39323
e-mail: juergen.winkler@uk-erlangen.de
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Prof. Ralf Linker
phone: +49 9131 85-33001
fax: +49 9131 85-34545
e-mail: ralf.linker@uk-erlangen.de
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Term

01.01.2016 - 30.06.2018

Project Manager

Prof. Dr. Jürgen Winkler

Department of Molecular Neurology


Prof. Dr. Ralf Linker

Department of Neurology

 
 
 
 
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Summary