IZKF-Project E22

IZKF

Head of Department:
Prof. Dr. med. André Reis

Swiprosin-1/EFhd2 in resilience to drug addiction

Drug addiction is a major psychiatric disorder. In the first Swiprosin-1/EFhd2 knock out model we found that EFhd2 works as resilience factor against addiction. We will now investigate how and where in the brain EFhd2 regulates the reinforcing effects of alcohol and methamphetamine, by controlling neurochemical, electrophysiological, and gene expression effects during addiction establishment. These insights will allow for a better understanding of resilience mechanisms against drug addiction.

Prof. Dr. Christian Müller
phone: +49 9131 85-36896
DECT: +49 9131 85-44593
e-mail: christian.mueller@uk-erlangen.de
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Prof. Christian Alzheimer
phone: +49 9131 85-22295
fax: +49 9131 85-22497
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PD Dr. Dirk Mielenz
phone: +49 9131 85-39105
fax: +49 9131 85-39343
e-mail: dmielenz@molmed.uni-erlangen.de
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Term

01.03.2016 - 31.08.2018

Project Manager

Prof. Dr. Christian Müller

Department of Psychiatry and Psychotherapy


Prof. Dr. Christian Alzheimer

Institute of Physiology and Pathophysiology


PD Dr. Dirk Mielenz

Department of Molecular Immunology

 
 
 
 
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Summary