IZKF-Project A71

IZKF

Head of Department:
Prof. Dr. med. André Reis

Viral modulation of the protein kinase ULK1

Research of the last years revealed that the cellular protein kinase ULK1 exerts critical regulatory functions at the intersection of autophagy, innate immunity and inflammatory disorders. We observed that ULK1 is strongly upregulated during human cytomegalovirus (HCMV) infection and a knockdown of ULK1 severely inhibited viral replication. This project aims to characterize how HCMV manipulates ULK1 since this may reveal a novel viral strategy to avoid hyperinflammation.

Prof. Dr. Thomas Stamminger
phone: +49 9131 85-26783
DECT: +49 9131 85-43657
fax: +49 9131 85-26493
e-mail: thomas.stamminger@viro.med.uni-erlangen.de
business card
 
Term

01.07.2016 - 31.12.2018

Project Manager

Prof. Dr. Thomas Stamminger

Institute of Clinical and Molecular Virology

 
 
 
 
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Summary