IZKF-Project A66

IZKF

Head of Department:
Prof. Dr. med. André Reis

Identification of antiviral restriction factors

We propose a systematic, unbiased approach at identifying cellular restriction factors of DNA viruses using the powerful CRISPR/Cas9 knockout technology, through a lentiviral sgRNA library targeting each human gene with several independent constructs. Our focus is on cellular factors that restrict or promote the replication of Herpesviruses and/or limit the growth of tumor cells transformed by KSHV and EBV. These factors represent primary therapeutic targets.

Prof. Dr. med. Armin Ensser
phone: +49 9131 85-22104
e-mail: armin.ensser@fau.de
business card
 
Term

01.07.2016 - 31.12.2018

Project Manager

Prof. Dr. Armin Ensser

Institute of Clinical and Molecular Virology

 
 
 
 
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Summary