Dr. Paolo Ceppi, leader of the Junior Research Group 1 "Understanding the plasticity of cancer cells" since August 2015, was awarded with the Young Investigator Award - Lung Cancer" by the International Association for the study of Lung Cancer (IASLC). The price is remunerated with 50.000 USD and is awarded once a year.
The Junior Group is focused on the mechanisms that regulate cancer plasticity and at studying the epithelial-to-mesenchymal transition, the cancer stem cells and the association between cancer differentiation and sensitivity to chemotherapy. Their aim is at identifying novel mechanisms that regulate the plasticity of cancer by the use of several cell and molecular biology techniques, mouse models, and the analysis of human samples as well as by –omics and high-throughput approaches.
The award was given to Dr. Paolo Ceppi for his contribution to the molecular characterization of lung tumors, which improved the therapeutic stratification of the patients and promoted the introduction of the histological determination in the clinical decision-making in non-small cell lung cancer. This funding will be used to support the current lab projects on determining the role of thymidylate synthase in the epithelial-to-mesenchymal transition in non-small cell lung cancer.
- Ceppi P et al. Cancer 2006, 107(7):1589-1596.
- Siddiqui A et al. The Journal of Pathology 2017, 242(2):221-233
Please find more information on the IASLC-website.