DNA-extraction platform for biobanking purposes

IZKF

Head of Department:
Prof. Dr. med. André Reis

DNA-extraction platform for biobanking purposes

Genetic and genomic studies for complex traits and clinical studies require high quality DNA-samples of probands as well as a rigorous and reliable handling and tracking of large numbers of samples. Starting in 2009, the IZKF core facility Z4 “DNA-Extraktionsplattform (Biobank)” was established offering quality controlled DNA-extraction from blood samples and other body fluids, their handling and aliquoting as well as their long-term archiving. The Core Unit has two large scale semi-automatic DNA-extraction platforms, a chemagic magnetic separation module I(Perkin Elmer) and an Autopure LS (Qiagen) and has a capacity of up to 10,000 samples/year. Both platforms yield high quality DNA samples suitable for all downstream applications such as PCR, SNP genotyping, microarray applications and next-generation sequencing. Part of the instrumentation was co-funded by the Erlangen University Comprehensive Cancer Centre. After conclusion of the IZKF funding in 2013 the core facility continues to offer its services financed through user fees.  

 
Contact
Dr. Cornelia Kraus
phone: +49 9131 85-26587
e-mail: cornelia.kraus@uk-erlangen.de
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Summary